He left this bustling city in an anguished manner.

他痛苦地离开了这个繁华的城市。

I noticed the anguished expression of this young man.

我注意到了这个年轻人的痛苦表情。

The girl suddenly had an anguished shout.

这个女孩突然痛苦地叫了起来。

She let out an anguished cry.

她发出了一声极为痛苦的叫喊。

Her heart anguished within her.

她的心中非常痛苦。

Writing is an anguished process for you. Why?

写作对你来说是极其痛苦的过程。为什么？

Mr. Zhao looked anguished at being ambushed by his friend.

被朋友伏击，赵亮看上去很痛苦。