Perforin, as its name implies, is able to target cell membrane perforation of the material.

穿孔素，顾名思义，就是能够在靶细胞膜上穿孔的物质。

Cytotoxic granules contain perforin and a group of serine proteases called granzymes in a proteoglycan matrix.

细胞毒性颗粒中含有包裹在蛋白多糖基质中的穿孔素和一类被称作颗粒酶的丝氨酸蛋白酶。

Results in normal mice, perforin was negative and connexin 43 was located in the intercalated disks of cardiac muscle.

结果：正常小鼠心肌中未见穿孔素阳性表达，连接蛋白43在心肌闰盘中呈阳性表达。

The observations of tumor necrosis factor and perforin reveal that cell mediated cytotoxic effects play an important role in the mechanism of this disease.

通过对肿瘤坏死因子及穿孔素的观察表明，细胞介导的细胞毒性作用在DMP的发病中起重要作用。

This review is about recent findings on the molecular biological characteristics of perforin, the mechanism of perforin-mediated apoptosis and the function of the apoptosis on anti-infective immunity.

这种由穿孔素介导的细胞凋亡机制在抗感染免疫等方面具有非常重要的作用。