the action or fact of ruining someone or something or of being ruined
毁灭;毁坏;没落;破产;堕落
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commercial malpractice causes the ruination of thousands of people .商业上的不端行为造成成千上万人倾家荡产。
 
the state of being ruined
毁灭(或破败、倾圮、没落的)状态
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the headquarters fell into ruination .总部已成一片废墟。
 
"mid 17th cent.:  from obsolete